A distinct type of cell in myocardium: interstitial Cajal-like cells (ICLCs)
نویسندگان
چکیده
منابع مشابه
A distinct type of cell in myocardium: interstitial Cajal-like cells (ICLCs)
The existence of a novel type of interstitial cells in the heart, interstitial Cajal-like cells (ICLCs), had been described for the first time in 2005. Their identification was mainly based on ultrastructural criteria: very long (tens up to hundreds of micrometres) and moniliform prolongations, which are extremely thin (less than 0.2 microm), below the resolving power of light microscopy. Myoca...
متن کاملInterstitial Cajal-like cells (ICLC) in atrial myocardium: ultrastructural and immunohistochemical characterization
We have previously reported (Hinescu & Popescu, 2005) the existence of interstitial Cajal-like cells (ICLC), by transmission electron microscopy, in human atrial myocardium. In the present study, ICLC were identified with non-conventional light microscopy (NCLM) on semi-thin sections stained with toluidine blue and immunohistochemistry (IHC) for CD117/c-kit, CD34, vimentin and other additional ...
متن کاملInsights into the interstitium of ventricular myocardium: interstitial Cajal-like cells (ICLC)
We have previously described interstitial Cajal-like cells (ICLC) in human atrial myocardium. Several complementary approaches were used to verify the existence of ICLC in the interstitium of rat or human ventricular myocardium: primary cell cultures, vital stainings (e.g.: methylene blue), traditional stainings (including silver impregnation), phase contrast and non-conventional light microsco...
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Traditional interstitial cells of Cajal (ICC) are present in the digestive tube and are supposed to act as pacemakers and neuromodulators. However, interstitial Cajal-like cells (ICLCs) were found outside the gastrointestinal tract, in various organs (e.g. ureter, bladder, fallopian tube, uterus, pancreas, mammary gland, myocardium etc.) and looking for such ICLC is a priority in our laboratori...
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CONTEXT The discovery and subsequent ultrastructural characterization of the interstitial Cajal like cells (now called telocytes) in virtually every anatomic sites of the human body, by Laurentiu M Popescu and co-workers, have dramatically improved the understanding the function of these cells and pathogenesis of extragastrointestinal stromal tumors (EGIST). Pancreatic extragastrointestinal str...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2009
ISSN: 1582-1838
DOI: 10.1111/j.1582-4934.2008.00668.x